Alex Y Strongin Selected Research

proteinase In

6/2010	Microarray-based transcriptional and epigenetic profiling of matrix metalloproteinases, collagens, and related genes in cancer.
3/2003	Membrane type-1 matrix metalloproteinase functions as a proprotein self-convertase. Expression of the latent zymogen in Pichia pastoris, autolytic activation, and the peptide sequence of the cleavage forms.

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Alex Y Strongin Research Topics

Disease

59	Neoplasms (Cancer) 01/2018 - 01/2002
17	Breast Neoplasms (Breast Cancer) 07/2013 - 03/2002
14	Neoplasm Metastasis (Metastasis) 01/2017 - 01/2002
9	Infections 01/2015 - 01/2005
8	Fibrosarcoma 07/2013 - 04/2002
7	Pain (Aches) 01/2018 - 01/2012
6	Hyperalgesia 01/2022 - 06/2012
6	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 02/2013 - 07/2005
6	Anthrax 06/2010 - 01/2005
6	Carcinoma (Carcinomatosis) 01/2009 - 04/2002
5	Peripheral Nerve Injuries 01/2022 - 02/2015
5	Carcinogenesis 01/2015 - 12/2005
5	Glioma (Gliomas) 06/2011 - 01/2002
4	Neuralgia (Stump Neuralgia) 01/2020 - 06/2012
4	Demyelinating Diseases (Demyelinating Disease) 01/2018 - 01/2009
4	Multiple Sclerosis 01/2018 - 01/2009
3	Hypersensitivity (Allergy) 01/2020 - 02/2015
3	Melanoma (Melanoma, Malignant) 01/2017 - 06/2006
3	Inflammation (Inflammations) 09/2015 - 10/2009
3	Dengue (Dengue Fever) 02/2011 - 02/2007
3	Influenza in Birds (Avian Flu) 06/2010 - 07/2007
2	Wounds and Injuries (Trauma) 01/2018 - 09/2015
2	Zika Virus Infection 11/2017 - 01/2017
2	Edema (Dropsy) 02/2017 - 02/2006
2	Wallerian Degeneration 02/2017 - 06/2012
2	Colorectal Neoplasms (Colorectal Cancer) 02/2015 - 01/2015
2	Communicable Diseases (Infectious Diseases) 06/2012 - 07/2008
2	Neuroinflammatory Diseases 06/2012 - 08/2008
2	Glioblastoma (Glioblastoma Multiforme) 06/2011 - 05/2009
2	Hyperglycemia 04/2009 - 01/2007
2	West Nile Fever 12/2007 - 01/2006
2	Chromosomal Instability (Chromosome Stability) 01/2007 - 07/2005
2	Aneuploidy (Aneuploid) 11/2006 - 07/2005
2	Stroke (Strokes) 07/2005 - 06/2003
1	Chronic Pain 01/2022
1	Confusion (Bewilderment) 01/2020
1	Microcephaly 01/2018
1	Nervous System Diseases (Neurological Disorders) 01/2018
1	Fibromyalgia (Fibrositis) 01/2018

Drug/Important Bio-Agent (IBA)

52	Matrix Metalloproteinases (MMPs)IBA 03/2018 - 01/2002
42	Matrix Metalloproteinase 14 (MT1-MMP)IBA 02/2017 - 01/2002
21	Peptide Hydrolases (Proteases)FDA Link 01/2017 - 09/2002
13	Pharmaceutical PreparationsIBA 01/2018 - 07/2005
13	Proteins (Proteins, Gene)FDA Link 08/2014 - 09/2002
10	Peptides (Polypeptides)IBA 01/2020 - 01/2006
10	Myelin Basic ProteinIBA 01/2020 - 01/2009
9	FurinIBA 06/2010 - 03/2002
6	Metalloproteases (Metalloproteinases)IBA 01/2015 - 05/2004
6	CollagenIBA 01/2013 - 01/2003
5	AntigensIBA 02/2017 - 01/2005
5	IntegrinsIBA 09/2015 - 03/2002
5	EnzymesIBA 07/2013 - 06/2002
5	prinomastat (Ag3340)IBA 02/2013 - 05/2003
4	Integrin alphaVIBA 11/2003 - 03/2002
3	AutoantibodiesIBA 01/2022 - 01/2018
3	Serine Proteases (Serine Protease)IBA 01/2020 - 02/2007
3	EpitopesIBA 01/2018 - 06/2012
3	LigandsIBA 08/2016 - 11/2004
3	Tyrosine (L-Tyrosine)FDA Link 08/2014 - 03/2002
3	Tissue Inhibitor of Metalloproteinase-2IBA 03/2010 - 05/2009
3	Proprotein Convertases (Pro-Opiomelanocortin Converting Enzyme)IBA 10/2009 - 03/2003
3	Insulin (Novolin)FDA Link 11/2007 - 09/2006
3	anthrax toxin (anthrax lethal factor)IBA 07/2007 - 01/2005
3	Complement System Proteins (Complement)IBA 06/2006 - 03/2002
2	Glucose (Dextrose)FDA LinkGeneric 01/2018 - 04/2009
2	Indicators and Reagents (Reagents)IBA 01/2017 - 01/2013
2	CytokinesIBA 09/2015 - 05/2015
2	Protein Isoforms (Isoforms)IBA 09/2015 - 01/2009
2	Interleukin-17 (Interleukin 17)IBA 09/2015 - 06/2012
2	MethyltransferasesIBA 02/2015 - 01/2015
2	DNA (Deoxyribonucleic Acid)IBA 01/2015 - 01/2004
2	DisintegrinsIBA 01/2015 - 08/2014
2	Cadherins (E-Cadherin)IBA 01/2014 - 04/2002
2	Matrix Metalloproteinase InhibitorsIBA 02/2013 - 08/2008
2	Viral ProteinsIBA 11/2012 - 01/2012
2	PolyproteinsIBA 01/2012 - 06/2008
2	LuciferasesIBA 02/2011 - 04/2002
2	proteinase InIBA 06/2010 - 03/2003
2	Histones (Histone)IBA 06/2010 - 05/2009
2	matrix metalloproteinase 25IBA 05/2010 - 10/2009
2	LipidsIBA 10/2009 - 02/2004
2	Hemagglutinins (Hemagglutinin)IBA 07/2008 - 07/2007
2	ExotoxinsIBA 07/2007 - 01/2005
2	Protease Inhibitors (Protease Inhibitor)IBA 05/2007 - 12/2004
2	Cell Surface ReceptorsIBA 09/2006 - 03/2002
2	pericentrinIBA 12/2005 - 07/2005
2	beta CateninIBA 05/2004 - 04/2002
2	Integrin alphaVbeta3IBA 01/2004 - 05/2003
2	progelatinaseIBA 01/2004 - 11/2002
2	VitronectinIBA 05/2003 - 03/2002
1	xestospongin CIBA 01/2020
1	Adenosine Triphosphate (ATP)IBA 01/2018
1	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2018
1	Immunoglobulin M (IgM)IBA 01/2018
1	Immunoglobulin G (IgG)IBA 01/2018
1	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA 01/2018
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2018

Therapy/Procedure

15	Therapeutics 01/2022 - 03/2002
3	Injections 05/2012 - 01/2007
1	Immunotherapy 01/2022